2009 Fiscal Year Final Research Report
Mechanism of Transcriptional and Secretary Regulation in Gut Incretin Producing Cells.
| Project/Area Number |
20890011
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Metabolomics
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| Research Institution | Asahikawa Medical College |
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Principal Investigator |
FUJITA Yukihiro Asahikawa Medical College, 医学部, 助教 (20451461)
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| Project Period (FY) |
2008 – 2009
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| Keywords | インクレチン / GIP / GLP-1 / 転写因子 / 小腸糖代謝 / 甘味受容体 |
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| Research Abstract |
Two transcription factors Pdx1 and Pax6 play pivotal roles for GIP gene regulation. Some reports showed that the sweet taste receptor is involved in sugar-induced incretin secretion, however, we indicated that sweeteners, which surly bind to the receptor, do not enhance incretin release in rats.
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