2009 Fiscal Year Final Research Report
Analysis of role of periostin in cerebral function
| Project/Area Number |
20890046
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KOIBUCHI Nobutaka The University of Tokyo, 医学部・附属病院, 特任助教 (30456131)
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| Project Period (FY) |
2008 – 2009
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| Keywords | ペリオスチン / 脳梗塞 / 保護作用 |
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| Research Abstract |
Periostin is an extracellular matrix protein that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Recently, it was shown that periostin promotes cardiac repair and remodeling. However, it is unclear that periostin plays a role in improvement of cerebral function. Thus, we examined whether periostin promotes cerebral repair.
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Research Products
(4 results)
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[Journal Article] Hepatocyte growth factor, but not vascular endothelial growth factor, attenuated angiotensin II-induced EPC senescence2009
Author(s)
Sanada F, Taniyama Y, Azuma J, Iekushi K, Dosaka N, Yokoi T, Koibuchi N, Kusunoki H, Aizawa Y, Morishita R.
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Journal Title
Hypertension 53
Pages: 77-82
Peer Reviewed
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[Journal Article] Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis2009
Author(s)
Mori M, Nakagami H, Koibuchi N, Miura K, Takami Y, Koriyama H, Hayashi H, Sabe H, Mochizuki N, Morishita R, Kaneda Y.
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Journal Title
Mol. Biol. Cell 20
Pages: 3115-3124
Peer Reviewed
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