2009 Fiscal Year Final Research Report
Analysis of mechanisms of substances which inhibit Porphyromonas gingivalis biofilm formation
| Project/Area Number |
20890121
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Conservative dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
ASAHI Yoko Osaka University, 歯学部附属病院, 医員 (50456943)
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| Project Period (FY) |
2008 – 2009
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| Keywords | ポルフィロモナスジンジバリス / バイオフィルム / クオラムセンシング / 阻害薬オートインデューサー / modified Robbins device |
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| Research Abstract |
Inhibitory mechanisms of autoinducer (AI) analogues on Porphyromonas gingivalis, a major periodontal pathogen, were investigated. By chronological observation, AI analogues affected on P.gingivalis biofilm growth. There were no effects on initial attachment and matured biofilm.
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