2009 Fiscal Year Final Research Report
Elucidation of angiogenic factor dynamics in the structural control of regenerated bone and identification of new related genes
Project/Area Number |
20890137
|
Research Category |
Grant-in-Aid for Young Scientists (Start-up)
|
Allocation Type | Single-year Grants |
Research Field |
Surgical dentistry
|
Research Institution | Okayama University |
Principal Investigator |
MORITANI Norifumi Okayama University, 岡山大学病院, 医員 (60467751)
|
Project Period (FY) |
2008 – 2009
|
Keywords | VEGF / CCN2 / CTGF / 血管新生因子 / 結合組織成長因子 / マイクロアレイ |
Research Abstract |
During the phase when bone is most actively regenerating, the angiogenic factors-VEGF and CCN2/CTGF proteins-are localized in osteoblasts, vascular endothelial cells, and osteoclasts near the regenerated bone. These proteins have been suggested to control bone formation and resorption and to synergistically promote bone regeneration. One hundred seventy-one candidate genes were extracted whose expression changes were related to the CCN2/CTGF gene.
|
Research Products
(5 results)
-
[Journal Article] 超高気孔率ハイドロキシアパタイトのラット頭蓋骨骨欠損部での組織学的、X線学的観察-骨形成過程の予備的研究-2008
Author(s)
植野高章, 平田あずみ, 脇本真理, 本多浩三, 白数信明, 澤木聖子, 太田晃子, 加納みわ, 森谷徳文, 松村達志, 水川展吉, 菅原利夫
-
Journal Title
日本顎顔面インプラント学会雑誌 6(3)
Pages: 205-211
-
[Journal Article] 当科における歯科インプラント前処置としての骨増量術を行った症例の病診連携の検討2008
Author(s)
植野高章, 平田あずみ, 脇本真理, 本多浩三, 白数信明, 澤木聖子, 太田晃子, 加納みわ, 森谷徳文, 松村達志, 水川展吉, 菅原利夫
-
Journal Title
日本顎顔面インプラント学会雑誌 6(3)
Pages: 219-222
-
[Presentation] Clinical and histological study in alveolar bone following post-extraction socket augmentation using Master Graft○R granules.2010
Author(s)
M. Wakimoto, T. Ueno, A. Hirata, T. Aghaloo, P.K. Moy, N. Shirasu, A. Ota, N. Moritani, M. Wakimoto, K. Sano, T. Yamada
Organizer
Academy of Osseointegration
Place of Presentation
Orland
Year and Date
20100304-20100306
-
-