2009 Fiscal Year Final Research Report
Lineage tracing of EPPK1-expressing cells : toward the elucidation of the mechanisms of pancreas regeneration
| Project/Area Number |
20890172
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Metabolomics
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| Research Institution | Kumamoto University |
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Principal Investigator |
MIKI Rika Kumamoto University, 発生医学研究所, COEリサーチアソシエイト (30516133)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 糖尿病 / 膵再生 / 膵β細胞 |
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| Research Abstract |
The expression of Eppk1 was found in the islet cells during the regeneration process. To genetically trace the EPPK1 expressing cells in the regeneration, we have attempted to establish transgenic mouse lines and I have obtained several EPPK1-CreER transgenic mouse lines. EPPK1-CreER : Z/EG mice were injected with tamoxifen (Tm). After Tm injection, I checked GFP expression.
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