2009 Fiscal Year Final Research Report
Nested case-control study to clarify a preventive factor of lung cancer.
| Project/Area Number |
20890291
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Public health/Health science
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| Research Institution | National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East |
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Principal Investigator |
SHIMAZU Taichi National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 予防研究部, 研究員 (00466202)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 肺癌 / イソフラボン / 疫学 / コホート研究 |
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| Research Abstract |
1) We investigated the association between isoflavone intake and lung cancer risk in a prospective cohort study. Isoflavone intake may be associated with a decreased risk of lung cancer in never smokers only. 2) We conducted a nested case-control study among women within the cohort, and found an inverse association between plasma level of genistein and lung cancer risk. The associations of isoflavone assessed by different methods with a decreased risk of lung cancer support the possibility that isoflavone is a preventive factor of lung cancer.
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