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2023 Fiscal Year Final Research Report

An exploratory study of the neural basis of intention understanding in rodents

Research Project

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Project/Area Number 20H01780
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 10040:Experimental psychology-related
Research InstitutionUniversity of Human Environments (2021-2023)
Tohoku University (2020)

Principal Investigator

Takano Yuji  人間環境大学, 総合心理学部, 教授 (00424317)

Co-Investigator(Kenkyū-buntansha) 笠原 好之  東北大学, 医学系研究科, 講師 (20511835)
Project Period (FY) 2020-04-01 – 2024-03-31
Keywords意図理解 / 動物モデル / 神経基盤 / 帯状回 / マウス / ラット
Outline of Final Research Achievements

The neural basis of intention understanding, which has been studied mainly in primates, including humans, was addressed by setting up behavioural experiments in rodents. As a result, we succeeded in developing behavioural experiments in rats and mice, which are model animals for human behaviour. In addition, we were able to observe behavioural disorders in autistic model mice in those behavioural experiments, demonstrating the validity of the task. The developed behavioural experiments were then used to promote experiments on the local disruption of brain regions related to the social brain and experiments on the recording of neural activity. In particular, we have been able to study the cingulate gyrus in rodents, which is increasingly understood as the neural basis of cognition, emotion and social behaviour in humans.

Free Research Field

実験心理学

Academic Significance and Societal Importance of the Research Achievements

高次な心的機能についての動物モデルの開発は遅れている。これまで社会行動のげっ歯類モデル実験では、他個体を認識することにとどまっており、その意図にまでは踏み込むことはできなかった。本研究の学術的意義は、この未到の領域に、げっ歯類の行動実験を勧められたことにある。そして、研究を心理学の範囲にとどめないで、神経科学へと広げることに成功した点にある。実際に、いくつかの論文を公刊することができ、今後の研究の萌芽も多数残すことができている。また、意図理解の神経基盤において、人とげっ歯類において共通性を指摘することもできた点は、私たちの人間の生物に対する心観を刷新するとという社会的意義もある。

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Published: 2025-01-30  

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