Magentic sparation of antibiotics and application to anaerobic digesion for resistant bacteria pandemic in livestock environment

2023 Fiscal Year Final Research Report

• Project/Area Number: 20H03107
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Review Section: Basic Section 41040:Agricultural environmental engineering and agricultural information engineering-related
• Research Institution: Kobe University
• Principal Investigator: Ihara Ikko 神戸大学, 農学研究科, 教授 (50396256)
• Co-Investigator(Kenkyū-buntansha): 間世田 英明 国立研究開発法人産業技術総合研究所, 生命工学領域, 上級主任研究員 (10372343) ; 清水 和哉 東洋大学, 生命科学部, 教授 (10581613) ; 梅津 一孝 帯広畜産大学, 畜産学部, 教授 (20203581)
• Project Period (FY): 2020-04-01 – 2023-03-31
• Keywords: 家畜糞尿 / 動物用抗菌剤 / 抗生物質 / 嫌気性消化 / 薬剤耐性菌 / 磁気分離

Outline of Final Research Achievements

In order to establish a method for controlling antibiotic-resistant bacteria discharged from livestock facilities, the removal of residual antibiotics by magnetic separation of antibiotics in wastewater containing animal manure and a method for reducing antibiotic-resistant bacteria by anaerobic digestion were investigated. Factors contributing to the removal rate were found in magnetic seeding of antibiotics in solutions containing high concentrations of organic matter, such as livestock manure solutions. Furthermore, the risk of emergence of antibiotic resistant bacteria, i.e. mutation risk of resistant genes, was assessed using actual wastewater, and dynamic changes in wastewater treatment performance and microbial communities were analyzed to find the minimum antibiotic concentration that would not affect the microbial community structure and wastewater treatment performance.

Free Research Field

農業環境情報工学

Academic Significance and Societal Importance of the Research Achievements

得られた研究成果は，ワンヘルスアプローチが期待される抗生物質耐性菌対策において畜産環境分野から直接的に貢献できる知見を含むことから，社会的な意義は大きいと考えられる。また，磁気力の環境応用を含むことから磁気科学の裾野を広げることにも寄与していると考えられ，学術的な意義も大きい。