Ultra-sensitive molecular sensing using plasmonic nanomaterials that can be switched on and off

2022 Fiscal Year Final Research Report

• Project/Area Number: 20K05280
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 28030:Nanomaterials-related
• Research Institution: National Institute for Materials Science
• Principal Investigator: SHINGAYA Yoshitaka 国立研究開発法人物質・材料研究機構, 国際ナノアーキテクトニクス研究拠点, 主任研究員 (40354344)
• Project Period (FY): 2020-04-01 – 2023-03-31
• Keywords: 酸化タングステンナノロッド / 増強ラマン散乱 / マルチプローブ原子間力顕微鏡

Outline of Final Research Achievements

The on-off switching of Raman scattering enhancement effect by tungsten oxide nanorods with two-dimensional conducting layers was investigated in detail in order to develop nanoprobes that can identify and detect single molecules adsorbed on active sites of the nanorods. The electrical properties of a single tungsten oxide nanorod were characterized in air using a multiple-probe atomic force microscope. The obtained current-voltage curve showed a unique characteristic that the resistance increased with the application of voltage. We conclude that this is due to the disappearance of two-dimensional conducting layers caused by intercalation of protons, which results in higher resistance.

Free Research Field

ナノ材料科学

Academic Significance and Societal Importance of the Research Achievements

本研究では、分子１個を識別検出できるナノプローブの開発において重要なラマン散乱増強効果のオンオフスイッチングメカニズムについて詳細に検討している。極微量の分子が重要な役割を果たす生体システムの微視的理解において、非常に重要な解析ツールを提供することに繋がる。学術的にはラマン散乱増強に金属ではなく、ニ次元導電面を有する酸化タングステンを用いる点が新しく、意義があると考えている。