Improvement of broiler meat production based on identification of causative agents of colibacillosis in chickens

2022 Fiscal Year Final Research Report

• Project/Area Number: 20K06432
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 42020:Veterinary medical science-related
• Research Institution: Tottori University
• Principal Investigator: Murase Toshiyuki 鳥取大学, 農学部, 教授 (20229983)
• Project Period (FY): 2020-04-01 – 2023-03-31
• Keywords: 鶏大腸菌症 / ブロイラー / 病原性 / 系統解析

Outline of Final Research Achievements

Colibacillosis in chickens is associated with reduction in meat and egg production and high mortality, resulting in significant economic losses to the poultry industry. It is considered that colibacillosis is caused by virulent strains of Escherichia coli although the characteristics the strains were unsure. In the present study, the prevalence of phylogroup F among colibacillosis-related isolates was significantly higher than that 32 among healthy chicken-related isolates. Therefore, the results suggest that immediate detection of E. coli strains with phylogroup F in chicken farms contributes to the prevention of colibacillosis and improved production.

Free Research Field

獣医細菌学

Academic Significance and Societal Importance of the Research Achievements

鶏の大腸菌症の原因となる大腸菌を特徴づける菌の性質はこれまで明らかでなかったため、診断や発生予防策の確立が困難である。このことは、人の腸管出血性大腸菌症の原因菌が志賀毒素（ベロ毒素）を産生することが指標となっている状況と、明らかに異なる。本研究における遺伝学的な解析の結果、大腸菌症の鶏から分離された大腸菌の多くが系統発生グループFと称される群に属することが明らかとなったことから、養鶏場で検出された大腸菌のグループを調べることにより本症の予防に私することが可能と考えられた。