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2020 Fiscal Year Research-status Report

The role of non-allelic gene conversion in the evolution of Transposable Elements

Research Project

Project/Area Number 20K06761
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

FAWCETT JEFFREY  国立研究開発法人理化学研究所, 数理創造プログラム, 上級研究員 (50727394)

Co-Investigator(Kenkyū-buntansha) 印南 秀樹  総合研究大学院大学, 先導科学研究科, 教授 (90444140)
Project Period (FY) 2020-04-01 – 2024-03-31
KeywordsTransposable Element / Gene conversion
Outline of Annual Research Achievements

Using a previously developed framework to simulate the evolution of Transposable Elements (TEs), we performed simulation of the sequence evolution of TEs to better understand how TE families evolve. Specifically, we created a scenario where a species containing a TE family split in to two, and the TE family is evolving independently in the two different species. We then calculated the divergence between the TE families in the two different species at different time points under various different parameter settings. We are currently establishing a theoretical framework to describe the divergence between TE families in different species.

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

We have been able to perform the simulation of TE evolution and analyze the results of the simulation as planned.

Strategy for Future Research Activity

Based on the simulation results, we well establish a theoretical framework that describes the expected divergence between TE sequences in different species. Then, we will compare our theoretical results with TE sequences from various plant species that have been published and discuss how the TE families in each plant species have evolved. We will also implement the action of non-allelic gene conversion in our simulation framework.

Causes of Carryover

We have not been able to attend scientific meetings and hold on-site meetings due to the COVID-19. Instead, we will use the incurring amount to purchase computer softwares and tools to better facilitate teleworking and online communication.

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Published: 2021-12-27  

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