2022 Fiscal Year Final Research Report
Development of new breed inherited Kaga Ouren
| Project/Area Number |
20K07112
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 47050:Environmental and natural pharmaceutical resources-related
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
北村 雅史 城西大学, 薬学部, 准教授 (10825392)
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | 黄連 / 育種 / アルカロイド |
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| Outline of Final Research Achievements |
The purpose of this research is to develop a new variety of the herbal medicine "Coptis Rhizome" by finding naturally occurring hybrids and comparing them with pure strains such as Coptis japonica var. anemonifolia and C. japonica var. major to clarify the effects of hybridization and to improve the domestic self-sufficiency rate of the herbal medicine. The results of this research revealed that the species-dependent characteristics, such as content and coloring in C. japonica var. anemonifolia and C. japonica var. major were clarified and that the characteristics of both were inherited as the influence of hybridization. In addition, it was found that the hybrids grew vigorously in cultivation and that the harvested weight and beard root weight were larger than those of the pure strains.
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| Free Research Field |
生薬学，薬用植物学
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| Academic Significance and Societal Importance of the Research Achievements |
漢方薬の原料となる生薬のほとんどは中国からの輸入によって供給されている。安定的な漢方医療の持続には輸入に依存した体制から脱却しなければならないが，優良種苗の確保など多くの課題を抱えている。本研究で開発したオウレンの新品種は生産性が高く，医薬品としての品質も確保されたものであり，生薬の国内自給率の向上に寄与するものであると考えられる。
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