2023 Fiscal Year Final Research Report
Construction of an oral education and medication support system by pharmacists based on oral function evaluation utilizing tongue pressure values
| Project/Area Number |
20K07172
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 47060:Clinical pharmacy-related
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| Research Institution | Chiba University |
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Principal Investigator |
Sekine Yuko 千葉大学, 大学院薬学研究院, 教授 (30567350)
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| Co-Investigator(Kenkyū-buntansha) |
久保田 洋子 日本薬科大学, 薬学部, 教授 (80573394)
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| Project Period (FY) |
2020-04-01 – 2024-03-31
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| Keywords | 口腔機能 / 舌圧 / 口腔体操 / RSST / 服薬支援 / 嚥下障害 / とろみ剤 / エドキサバン錠 |
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| Outline of Final Research Achievements |
① Created oral exercises (healthy mouth exercises) and music to train the three types of muscles necessary for oral function in order to educate visitors and patients. Created educational materials for oral function training sessions for pharmacists and nursing facility workers, and held training sessions. ②Investigated oral function and autonomic function, and found no relationship between oral function (tongue pressure value, ODK) and skin water content. Oral function and tablet size were investigated, and it was found that thicker tablets were more difficult to swallow as the tongue pressure level decreased. ③The dissolution of edoxaban film-coated tablets and OD tablets immersed in a thickening agent was tested, and it was found that the dissolution of OD tablets was significantly delayed compared to that of film-coated tablets, and the dissolution was significantly delayed as the PH of the dissolution test solution decreased.
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| Free Research Field |
臨床薬学
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| Academic Significance and Societal Importance of the Research Achievements |
口腔機能維持・向上のための健口体操をどこでも行えるようになり、専門施設だけでなく薬局の健康フェアでもオーラルフレイル予防活動が可能となる。また、口腔機能の低下により服用できる錠剤の形状に制限のあることが明らかになり、薬剤師が患者の口腔機能に合わせた処方提案が可能となる。さらに、とろみ剤の使用により溶出が遅延する剤型のあることが明らかになり、現在嚥下困難者でよく処方されているOD錠を服用する場合、とろみ剤使用については注意が必要であることが明らかとなった。
本研究により、多くの薬局が口腔機能ケアを通して健康サポート活動に参画し、「未病」の地域住民の健康改善に貢献でき、薬局の新しい機能を確立できる。
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