2022 Fiscal Year Final Research Report
Establishment of an infrastructure for comprehensive analysis of infectious diseases using claims databases
| Project/Area Number |
20K07831
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 52010:General internal medicine-related
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| Research Institution | Jichi Medical University |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | 感染症疫学 / 医療ビッグデータ / 抗微生物薬 / インフルエンザ / HIV感染症 |
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| Outline of Final Research Achievements |
Using the nationwide and region-wide claims databases, we established an infrastructure for comprehensive, advanced analysis of epidemiology, with a particular interest in infectious diseases and general internal medicine. Our results showed that the number of oral antibiotics prescriptions has been decreasing since 2016. Also, there have been certain improvements in the quality of antibiotic use in dentistry. The number of non-coronavirus upper and lower respiratory tract infections and acute diarrhea has sharply decreased since the COVID-19 outbreak. We have also conducted a large-scale epidemiological analysis of influenza and HIV infection-associated diseases, including hepatitis and diabetes-related infections.
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| Free Research Field |
感染症学・総合内科
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| Academic Significance and Societal Importance of the Research Achievements |
抗菌薬耐性(AMR)対策2016-2020の効果判定を行い、次の目標指標に向けて取り組むにあたって基礎データとなりえる。歯科領域のデータは限られていたが、データギャップの補完を可能とした。新型コロナウイルス感染症に対する感染対策や行動制限は、様々な医療に一定の(気道感染症に対しては強い)インパクトを与えており、ポストコロナ時代の医療に向けた指標として利用可能である。インフルエンザ、HIV感染症(肝炎等を含む) 、糖尿病関連感染症の大規模疫学の中間解析からは、新規の知見が得られており、発展研究が期待できる。
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