2023 Fiscal Year Final Research Report
Methodology for 2 dimensional in-situ measurement of quality and intensity of BNCT beam
| Project/Area Number |
20K08050
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 52040:Radiological sciences-related
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| Research Institution | Kyoto Pharmaceutical University (2022-2023)
Hiroshima University (2020-2021) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
廣木 章博 国立研究開発法人量子科学技術研究開発機構, 高崎量子応用研究所 先端機能材料研究部, 併任 (10370462)
櫻井 良憲 京都大学, 複合原子力科学研究所, 准教授 (20273534)
遠藤 暁 広島大学, 先進理工系科学研究科(工), 教授 (90243609)
梶本 剛 広島大学, 先進理工系科学研究科(工), 助教 (70633759)
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| Project Period (FY) |
2020-04-01 – 2024-03-31
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| Keywords | 中性子捕捉療法 / 蛍光体 / 線量 / 線質 / 波長特性 |
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| Outline of Final Research Achievements |
In boron neutron capture therapy, a key-factor is the distribution of quantity and quality, i.e., linear energy transfer (LET) and relationship between beam quantity of thermal, epithermal, fast neutrons and gamma rays, of the incident beam. The present research aims at measuring 2-dimensional distributions of quality and quantity of the beam using the luminescence.
Consequently, the purpose was achieved by using the luminescence from BaFBr:Eu irradiated by the stimulating light with wave length of 532 nm and 650 nm. The measurement in 2-dimension was shown to be feasible by including minute powder of BaFBr:Eu in the laminate film. In addition, its usage as a bolus was suggested by sandwiching the film with the living-body-like materials or gel dosimeters.
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| Free Research Field |
医学物理学
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| Academic Significance and Societal Importance of the Research Achievements |
光刺激蛍光体の波長を原理を用いてビーム成分強度・線量・線質を一括して評価ことを目論む。蛍光体を2次元検出器（薄型・ボーラス）に構築する点、読取装置・解析法まで開発する点が特徴的である。
適用腫瘍や臨床数の増加による医学・生物学・化学・物理学の横断的な研究に波及する意義がある。
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