Reconstruction of dose distributions using PET images in heavy ion therapy

2020 Fiscal Year Research-status Report

• Project/Area Number: 20K08066
• Research Institution: National Institutes for Quantum and Radiological Science and Technology
• Principal Investigator: Mohammadi Akram 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 先進核医学基盤研究部, 主任研究員(任常) (10554735)
• Project Period (FY): 2020-04-01 – 2023-03-31
• Keywords: dose reconstruction / PET image / ion therapy

Outline of Annual Research Achievements

A library of dose data and PET data for C-11 beams with energies of 170, 210, 290 and 350 MeV/u for a PMMA phantom was made using Monte Carlo simulation (Phits code). The algorithm for converting PET data to dose distribution was constructed and its optimization is still under development. A ridge filter for a C-11 beam (350 MeV) with 2 centimeter of SOBP was designed and tested experimentally in the carbon therapy facility of the Heavy Ion Medical Accelerator in Chiba (HIMAC).

Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

The progress of the research was almost according to the original plan and there was no problem by now.

Strategy for Future Research Activity

For the next fiscal year, a ridge filter for C-12 beam with 2~3 cm SOBP will be designed and its performance will be optimized experimentally in the HIMAC. Meanwhile, optimization of the algorithm for dose estimation using PET data for both C-11 and C-12 beams will be continued for a PMMA phantom.

Causes of Carryover

There was no need to buy any items since the required items were available in our group.