2022 Fiscal Year Final Research Report
Novel hyperthermia using high-precision electromagnetic field simulation technology
| Project/Area Number |
20K08146
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 52040:Radiological sciences-related
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
黒田 輝 東海大学, 情報理工学部, 教授 (70205243)
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | 温熱療法 / ハイパーサーミア / サーマル ドーズ / 温熱治療計画 / 高精度放射線治療 / がん集学的治療 |
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| Outline of Final Research Achievements |
The major reasons for the lack of widespread use of hyperthermia can be summarized into the following three points: 1) poor concentration of heating in deep areas where many cancers exist, 2) delay in the development of a heating method (capacity-coupled heating) that takes advantage of the advantage of the Japanese, who tend to have thin body types, and 3) large differences in the achieved thermal dose, an objective measure of thermal dosage, among patients. 3) The achievement value of thermal dose, which is an objective measure of thermal dosage, varies widely among patients, resulting in individual differences in therapeutic effects.
This study is to plan hyperthermia according to patient body shape and target by using electromagnetic field simulation. Furthermore, it is to select more effective heating methods, predict the thermal dose that can be administered, and explore more scientifically the contribution of thermal therapy in the recent multidisciplinary treatment of cancer.
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| Free Research Field |
放射線腫瘍学
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| Academic Significance and Societal Importance of the Research Achievements |
Compared to molecular targeted drugs and immunotherapy, hyperthermia has high potential in terms of health economic benefits as an inexpensive method to improve anti-cancer efficacy. This is a valuable study for the use of hyperthermia as a further step toward multidisciplinary treatment.
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