2022 Fiscal Year Final Research Report
Quantitative assessment of myocardial fatty acid metabolism by SPECT and CT
| Project/Area Number |
20K08411
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 53020:Cardiology-related
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| Research Institution | Fujita Health University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
谷澤 貞子 藤田医科大学, 医学部, 客員教授 (30308902)
河合 秀樹 藤田医科大学, 医学部, 准教授 (30778361)
外山 宏 藤田医科大学, 医学部, 教授 (90247643)
市原 隆 藤田医科大学, 医学部, 教授 (90527748)
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | BMIPP / myocardial fatty acid / myocardial blood flow / myocardial CT / coronary CT |
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| Outline of Final Research Achievements |
<Results and Discussion> There was no difference in resting myocardial blood flow among the three groups (normal, infarct, dysfunction: hypokinesia). This was attributed to successful PCI in all cases. There was little relationship between resting blood flow and fatty acid dynamics. BMIPP visual accumulation (%UT) at the initial image showed a weakly significant positive correlation with K1 and a strong significant negative correlation with k2/K1. In the comparison between the three groups, it was difficult to evaluate the functional impairment due to %UT in the early stage of BMIPP, and it was considered necessary to evaluate the intake, excretion, excretion/intake ratio, and intake rate of BMIPP. <Conclusion> Quantitative measurement of myocardial fatty acid dynamics by BMIPP dynamic scan was considered useful for the evaluation of myocardial status (dysfunction).
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| Free Research Field |
Nuclear Cardiology
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| Academic Significance and Societal Importance of the Research Achievements |
Quantitative measurement of myocardial fatty acid dynamics by BMIPP dynamic scan was considered useful for the evaluation of myocardial status (dysfunction).
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