2023 Fiscal Year Final Research Report
Development of a new and safe exercise management plan to improve the prognosis of adolescents after Fontan surgery.
| Project/Area Number |
20K08417
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 53020:Cardiology-related
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| Research Institution | University of Miyazaki (2022-2023)
Fukuoka Children’s Hospital (2020-2021) |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2024-03-31
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| Keywords | フォンタン循環 / 運動 |
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| Outline of Final Research Achievements |
Due to the COVID-19 pandemic during the study period and the investigator's transfer of the institution, it was not possible to recruit patients as originally planned. However, a cardiopulmonary exercise test was performed under venous pressure measurement in a limited number of patients. In addition, we analyzed the changes in Fontan circulation when subjected to special breathing patterns (e.g., trumpet playing and singing), which have not been reported previously. We confirmed a tendency for central venous pressure to increase during trumpet playing in Fontan patients and a tendency for central venous pressure to increase less during singing, recorder, and other loads with a limited increase in intrathoracic pressure. Several relevant English-language papers were published during the study period, and the results of studies on exercise in Fontan patients were presented at the 56th Association for European Paediatric and Congenital Cardiology) in April 2023.
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| Free Research Field |
小児循環器学
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| Academic Significance and Societal Importance of the Research Achievements |
本研究は、Fontan術後患者の運動時血行動態の解明に役立つものであった。胸腔内圧が上昇させる負荷が、どの程度静脈圧に影響を与えるかは、本研究以前には報告のないものであった。今後も症例数を増やし、Fontan術後患者の遠隔期管理のエビデンス確立に努めたい。
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