2022 Fiscal Year Final Research Report

Verification of Risk Factors for Recurrence of Minimally Invasive Surgery for Cervical Cancer in Japan

Research Project

PDF

Project/Area Number	20K09641
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 56040:Obstetrics and gynecology-related
Research Institution	Osaka University
Principal Investigator	Kobayashi Eiji 大阪大学, 大学院医学系研究科, 講師 (50614773)
Co-Investigator(Kenkyū-buntansha)	上田豊大阪大学, 大学院医学系研究科, 講師 (10346215) 平松宏祐大阪大学, 医学部附属病院, 助教 (10650591) 三上幹男東海大学, 医学部, 教授 (30190606) 中川慧大阪大学, 大学院医学系研究科, 助教 (30650593) 金尾祐之公益財団法人がん研究会, 有明病院婦人科, 部長 (80372621) 中谷英仁静岡社会健康医学大学院大学, 社会健康医学研究科, 准教授 (80627670) 武隈宗孝静岡県立静岡がんセンター(研究所), その他部局等, 研究員 (80644062) 木村敏啓大阪大学, 大学院医学系研究科, 講師 (90584524)
Project Period (FY)	2020-04-01 – 2023-03-31
Keywords	子宮頸癌 / 低侵襲手術 / 腹腔鏡 / 多施設共同研究
Outline of Final Research Achievements	In 2016, we planned the “Survey of Laparoscopic Radical Hysterectomy as an Advanced Medical Care - JGOG 1081s -" in order to make this technique, which was approved as an advanced medical treatment, an insured treatment, and have collected perioperative results and short-term prognostic information on 258 cases of LRH from 22 institutions. In this study, we extended the observation period of the 1081s study and re-examined the details of surgical techniques and prognostic information. We also examined the relationship between surgical skill and prognosis by examining surgical videos of recurrent and non-recurrent cases as a case-control study. The results showed that more detailed surgical technique and prognostic information could be verified, and that surgical technique and prognosis were consistently related in the case-control study.
Free Research Field	婦人科腫瘍
Academic Significance and Societal Importance of the Research Achievements	本研究により、先進医療として行われた子宮頸がんの実態を示すことができた。いまだに議論されている子宮頸がんに対する低侵襲手術の是非を検証する前向研究JGOG1087s研究のプロトコール作成の骨子となり、今後の本邦における子宮頸がん診療における貴重なエビデンスとなった。