Development of Antibacterial Dental Restorations Using Nanostructured Titania Nanosheets

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K10049
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 57050:Prosthodontics-related
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: Nozaki Kosuke 東京医科歯科大学, 大学院医歯学総合研究科, 講師 (00507767)
• Co-Investigator(Kenkyū-buntansha): 陳 鵬 東京医科歯科大学, 生体材料工学研究所, 助教 (70708388)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: チタニア / 表面電荷 / ナノ粒子 / 色素分解 / 光触媒活性

Outline of Final Research Achievements

In this study, we demonstrate a safe and facile method for fabricating single-nanometer-sized titania nanosheets (NSs) and reveal that NS0.3 exhibits the highest photocatalytic activity for dye degradation. Our findings suggest that the enhanced activity is primarily attributed to the increased surface area and improved adsorption capacity due to size reduction, rather than the amount of generated active oxygen species. Furthermore, we successfully enhance the photocatalytic activity of TiO2 nanosheets by inducing surface charge without introducing dopants through electrochemical polarization treatment. This enhancement is ascribed to the improved adsorption and decomposition of dyes on the TiO2 nanosheets.

Free Research Field

無機生体材料学

Academic Significance and Societal Importance of the Research Achievements

シングルナノメートルサイズに改良したチタニアナノシートっは，歯科診療領域内のような紫外線量に制限のある場所での汚染物の洗浄作用に有効な可能性が示唆された．また，表面電荷を誘起したTiO2ナノシートを応用することで高い清潔観念が求められる歯科診療領域内の歯科環境材料において脱色，殺菌，および防汚の向上が期待された．本研究で得られた知見は材料学的に非常に重要な知見であり，今後の歯科診療内での環境浄化の発展に寄与するものと考えられる．