2022 Fiscal Year Final Research Report
A cohort study for identifying risk factors of periodontal disease in Japanese
| Project/Area Number |
20K10249
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 57080:Social dentistry-related
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| Research Institution | Ehime University |
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Principal Investigator |
Tanaka Keiko 愛媛大学, 医学系研究科, 准教授 (40341432)
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| Co-Investigator(Kenkyū-buntansha) |
三宅 吉博 愛媛大学, 医学系研究科, 教授 (50330246)
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | 前向きコーホート研究 / 歯周疾患 / リスク要因 / 中高年 / 生活習慣病 / 口腔機能 |
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| Outline of Final Research Achievements |
The Aidai Cohort Study (AICOS) is an ongoing prospective cohort study in Japan. We enrolled 10376 participants aged 20-95 years until March in 2024. At the baseline survey, using a self-administered questionnaire, information on various lifestyle factors such as smoking, drinking, and physical activity was collected. In addition, we performed health examinations.
We found that higher number of teeth was associated with decreased prevalence of hearing impairment. Among women, but not men, tongue strength was associated with lower prevalence of mild cognitive impairment. Further studies are needed to clarify the causality of the observed associations.
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| Free Research Field |
医歯薬学
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| Academic Significance and Societal Importance of the Research Achievements |
口腔内の健康状態が全身の健康へ与える影響について、日本人を対象としたエビデンスは、あまり多くはない。愛大コーホート研究では、口腔の健康に関する情報を詳細に収集しており、全身疾患との関連について、多くのエビデンスの産出が期待できる。今回、コーホート研究の一部の対象者のデータを活用した解析結果から、喪失歯の減少によって、難聴を予防できる可能性や、口腔機能の一つである咬合力を保つことにより、軽度認知機能障害を予防できる可能性が示唆された。
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