Significance of prolonged sedentary bouts in chronic kidney disease

2022 Fiscal Year Final Research Report

• Project/Area Number: 20K11557
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 59040:Nutrition science and health science-related
• Research Institution: Kagawa University
• Principal Investigator: Miyatake Nobuyuki 香川大学, 医学部, 准教授 (30510705)
• Co-Investigator(Kenkyū-buntansha): 片山 昭彦 四国学院大学, 社会学部, 教授 (00435075) ; 鈴木 裕美 香川大学, 医学部, 助教 (00644733)
• Project Period (FY): 2020-04-01 – 2023-03-31
• Keywords: 連続した座位行動バウト / 慢性腎臓病 / 連続座位行動 / 慢性血液透析

Outline of Final Research Achievements

We investigated the significance of prolonged sedentary bouts in patients on chronic kidney disease (CKD). In patients on chronic hemodialysis, prolonged sedentary bouts were closely associated with health-related quality of life (HRQOL) and deaths by cross-sectional and cohort study, especially in non-hemodialysis days. However, in subjects undergone annual health check-up, prolonged sedentary bouts were not associated with HRQOL in cross-sectional study. Therefore, prolonged sedentary bouts were important factor for deaths in CKD, especially in chronic hemodialysis patients. Strategy for reducing prolonged sedentary bouts would be beneficial for patients on chronic hemodialysis in the future.

Free Research Field

衛生学

Academic Significance and Societal Importance of the Research Achievements

慢性血液透析患者では、特に透析日では治療のため臥位にならなければならないことが多く、身体活動を増加させることは困難であることが予想される。今回、慢性血液透析患者において、連続した座位行動バウトが健康関連QOLや生命予後と関係したことから、今後特に非透析日における連続した座位行動バウトを減らすことが生命予後の改善に寄与するものと思われた。