2022 Fiscal Year Final Research Report
Fundamental study on thermal and hydrodynamic effect of laser induced bubble for TUL on surrounding field
Project/Area Number |
20K12610
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Review Section |
Basic Section 90110:Biomedical engineering-related
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Research Institution | Kanazawa Institute of Technology |
Principal Investigator |
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Project Period (FY) |
2020-04-01 – 2023-03-31
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Keywords | 結石破砕 / レーザ誘起気泡 / CEM43℃ / TUL / URS / Bubble dynamics |
Outline of Final Research Achievements |
TUL or URS is a typical method of lithotripsy. In this treatment method, a medical doctor irradiates a pulsed laser through an optical fiber to break up the stones. There are two mechanisms of stone breakage: photoacoustic (impact during bubble formation and collapse) and photothermal (heat from the laser). On the other hand, the movement of the stone to be crushed and the generation of thermal damage to the surrounding tissue due to the heat of the irradiated pulsed laser energy are problematic. Through this research project, we clarified the behavior of stones and bubbles by simulating the treatment condition, and showed the possibility of thermal damage to the surrounding tissues by measuring temperatures.
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Free Research Field |
流体工学,生体医工学
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Academic Significance and Societal Importance of the Research Achievements |
TULを用いた結石破砕において最終的に患者および医師に負担の少ない手術法を提案することが本研究の目的である.臨床医師は症例,すなわち経験が多いほど治療スキルが高くなる.これは経験つまり工学分野における実験を繰り返しているからである.この作業をできるだけ少なくできれば,患者の負担及び医師の負担の軽減につながる.本研究成果で示した気泡挙動,結石の挙動,熱傷領域の評価によって,医師の手術における効果的およびリスクの高いレーザ照射条件を提示できた.この知見は臨床医師の負担軽減と患者へのリスク低減につながると考える.
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