2022 Fiscal Year Final Research Report
Research of preparation conditions of made-to-order variable viscosity enteral nutrient for feedback to nursing care.
| Project/Area Number |
20K12770
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Review Section |
Basic Section 90150:Medical assistive technology-related
|
|---|
| Research Institution | Tokai University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2020-04-01 – 2023-03-31
|
| Keywords | 粘度可変型栄養剤 / 液体栄養剤症候群 / アルギン酸ナトリウム凝固剤 / キサンタンガム系増粘剤 / 経腸栄養ポンプ移送 / 乳タンパク / カルシウムイオン / 人工胃液 |
|---|
| Outline of Final Research Achievements |
For the purpose of prevention of liquid formula syndrome and feedback to nursing care, we conducted the research to clarify the preparation method and administration precautions of "made-to-order variable viscosity enteral nutrient" according to the patient's pathology. Only the milk protein-containing commercially available liquid enteral nutrient was aggregated by the react with the artificial gastric juice (pH1.2). Therefore, sodium alginate as coagulant, xanthan gum-based thickener were added to a liquid nutrient to make a "made-to-order variable viscosity enteral nutrient". The viscosity increased in proportion to the concentration of calcium and potassium in the liquid nutrient. Moreover, dosing time was also changed significantly.
Furthermore, in the reaction between the "made-to-order variable viscosity enteral nutrient" and the artificial gastric juice, there were differences in the state of aggregation and coagulation depends on the coagulant and liquid enteral nutrient.
|
| Free Research Field |
応用化学工学
|
| Academic Significance and Societal Importance of the Research Achievements |
本研究により、乳タンパクが含まれる液体栄養剤は胃液で凝集すること、アルギン酸ナトリウムの添加による凝固の促進・キサンタンガム系増粘剤の添加による離水分抑止効果が得られること、さらに液体栄養剤や凝固剤の種類と組み合わせにより粘度が大きく変化することなど、成果として「患者の病態に応じたオーダーメイド粘度可変型栄養剤」の自己調製条件や問題点も明らかとしたことは、学術的に意義のあることである。
本研究成果は、「患者の病態に応じたオーダーメイド粘度可変型栄養剤を自己調製」する際の諸情報を患者と家族、医療従事者や介護支援者へ提供できることから、社会的にも意義のある研究成果と考えられる。
|
