Genome wide analysis in African rice and establshment of GWAS catalogs

2022 Fiscal Year Final Research Report

• Project/Area Number: 20K15503
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 39010:Science in plant genetics and breeding-related
• Research Institution: Okayama University
• Principal Investigator: Furuta Tomoyuki 岡山大学, 資源植物科学研究所, 助教 (70774008)
• Project Period (FY): 2020-04-01 – 2023-03-31
• Keywords: アフリカイネ / 全ゲノム連関解析 / 量的形質 / バイオインフォマティクス

Outline of Final Research Achievements

Whole genome association study was performed on 172 lines of O. glaberrima cultivars, and candidate loci for genes contributing to trait diversity within the O. glaberrima cultivars for various agronomic traits including seed size and days to heading were detected. On the other hand, the trait diversity of O. glaberrima differed among the origin of country of each variety, indicating a strong population structure in the tested population. We also developed a GWAS cataloging tool to organize GWAS results and efficiently search for causal genes. In addition, we developed a tool to correct errors in genotype data determined by next-generation sequencers.

Free Research Field

遺伝育種

Academic Significance and Societal Importance of the Research Achievements

本研究で同定されたO. glaberrimaの農業形質に関与する遺伝子座が同定されたことで、O. glaberrimaの遺伝子をO. sativa育種に利用する基盤情報が整備された。また、O. glaberrimaを育種することで新たな食料資源として活用する可能性も開かれた。さらに、GWASカタログ化ツールや遺伝子型データエラー修正ツールなど、遺伝育種研究を支える新たな解析ツールが生み出され、今後の当該分野の発展を支える基盤が構築された。