2022 Fiscal Year Final Research Report
Role of central natriuretic peptides in invasion into freshwater environment
| Project/Area Number |
20K15604
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 40040:Aquatic life science-related
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| Research Institution | Okayama University |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | ウナギ / 変態 / ホルモン / 進化 |
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| Outline of Final Research Achievements |
We identified mRNA localization of CNP4 and a newly identified CNP4b in the eel brain, and experimentally revealed their behavioral and physiological functions. When compared to medaka and zebrafish, it was unexpectedly revealed that after the emergence of CNP4b during the evolution of bony fish, there was a temporary functional division between CNP4a and CNP4b, which disappeared in fish that evolved later than eels. These findings were published in Cell and Tissue Research (impact factor: 4.061) and were highly regarded by researchers not only in fisheries science but also in medical and life sciences. Therefore, this study proceeded smoothly for the most part.
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| Free Research Field |
海洋生物学
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| Academic Significance and Societal Importance of the Research Achievements |
魚類の進化プロセスに関する基礎的知見が得られた。また、ウナギの保全に関わる知見が得られた。
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