CGA (Comprehensive Geriatric Assessment)-based Personalized Care for Older Adults with Cancer

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K16540
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 52010:General internal medicine-related
• Research Institution: National Hospital Organization, Kyushu Cancer Center
• Principal Investigator: Nishijima Tomohiro 独立行政法人国立病院機構(九州がんセンター臨床研究センター), その他部局等, 老年腫瘍科医師 (20840549)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: 高齢者総合的機能評価 / CGA / FI-CGA-10 / 予備能力 / 高齢がん患者

Outline of Final Research Achievements

This was a prospective observational study of older adults with cancer who underwent a Comprehensive Geriatric Assessment (CGA) at a geriatric oncology service. This study has revealed that a postoperative complication risk can be estimated using information derived from the multi-dimentional evaluation of health status through CGA. Additionally, we have developed an objective assessment method for the pre-treatment capacity to cope with the psychophysical stress in older adults with cancer undergoing consideration for various forms of cancer treatment, utilizing a method known as the Frailty Index. Finally, our study has demonstrated that integration of CGA into the care of older adults with cancer facilitates individualized treatment decision-making and indicated the potential for improvement in treatment outcomes.

Free Research Field

老年腫瘍学

Academic Significance and Societal Importance of the Research Achievements

高齢がん患者では患者ごとに副作用や合併症の危険性そして予備能力(どの程度の心身のストレスに耐えられるか) が大きく異なる。このため、本研究で検討したCGAで得られる情報をもちいた術後合併症予測ツールやFrailty Indexによる予備能力の定量化が重要である。このような評価を治療方針決定前に行うことで、一人ひとりに最適な治療の選択につながる。さらに、高齢がん患者のアウトカムの改善を目指して、評価で見つかった健康上の問題点に多職種で介入することができる。