2022 Fiscal Year Final Research Report
Elucidation of epileptogenesis in acute stroke (Multicenter Prospective Observational Study)
| Project/Area Number |
20K16603
|
|---|
| Research Category |
Grant-in-Aid for Early-Career Scientists
|
| Allocation Type | Multi-year Fund |
|---|
| Review Section |
Basic Section 52020:Neurology-related
|
|---|
| Research Institution | Kumamoto University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2020-04-01 – 2023-03-31
|
| Keywords | 脳卒中 / てんかん / 脳波 |
|---|
| Outline of Final Research Achievements |
We are prospectively registering the frequency of acute symptomatic seizures and post-stroke epilepsy in patients hospitalized for acute cerebral infarction by collecting patient background, imaging, and electroencephalographic findings. As a report of our research, a review article titled "Clinical Neurophysiology of acute symptomatic seizures in stroke patients" was accepted for publication in Clinical Neurophysiology, the official journal of the Japanese Society of Clinical Neurophysiology, outlining acute symptomatic seizures in acute stroke and the subsequent onset of epilepsy. He plans to submit a review article on the development of epilepsy and dementia after stroke to an international journal.
|
| Free Research Field |
神経
|
| Academic Significance and Societal Importance of the Research Achievements |
本研究を介して，急性期脳血管障害における急性症候性発作及びその後のてんかん発症についての知見が深まり，てんかん発症の病態解明の一助となることが予測される，また急速に脳卒中後てんかんにおいては，てんかん非合併患者よりも，認知機能が低下することが知られており，脳卒中後てんかんと血管性認知症の発症機序は、脳卒中患者では重複する傾向があることが示唆された．脳卒中後のてんかんや認知症について，さらに研究調査することで，高齢化社会となった日本の，健康寿命の増進に将来的に寄与すると考えられる．
|
