2023 Fiscal Year Final Research Report
Development of Pulmonary Ventilation and Blood Flow Imaging System Using Low Dose X-ray Fluoroscopic Imaging
| Project/Area Number |
20K16709
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 52040:Radiological sciences-related
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| Research Institution | Teikyo University (2020, 2022-2023)
Juntendo University (2021) |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2024-03-31
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| Keywords | 画像診断 / 透視 / 動態解析 / 肺血流 |
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| Outline of Final Research Achievements |
A healthy volunteer study was conducted. Automatic extraction tended to be difficult because of the lack of variation in the periodic components when original fluoroscopic images are visually bright. Therefore, it is necessary to manually adjust the tube voltage to obtain dark images. Fluoroscopic images taken under respiratory distress also tended to make analysis more difficult.
In the respiratory images, the effects of the ribs could not be fully removed, and results could not be obtained within this research period. In the area of perfusion imaging, we are in the process of collecting cases of patients with pulmonary emboli, and have obtained images that appear to be due to decreased blood flow. This may contribute to the diagnosis of pulmonary embolism.
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| Free Research Field |
画像診断・IVR
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| Academic Significance and Societal Importance of the Research Achievements |
呼吸機能に関しては研究期間内に結論付けることはできなかったが、肋骨の影響を除することができれば、肺気腫の診断や、呼吸器外科術前の癒着評価など、動態的な評価が必要な場面で有用となる可能性がある。
血流画像に関しては今回塞栓部位の血流低下を疑う解析結果が出たため、今後肺塞栓の診断に寄与できる可能性がある。完全に肺塞栓症の診断に置き換わる可能性は低いが、造影剤を使わずに検査ができるため、造影前のスクリーニング検査となりうる可能性がある。
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