Influence of balance of protein and non-protein calorie on physical prognosis in ICU patients

2021 Fiscal Year Final Research Report

• Project/Area Number: 20K17784
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 55050:Anesthesiology-related
• Research Institution: Kochi University
• Principal Investigator: Katsumata Yoshifumi 高知大学, 教育研究部医療学系臨床医学部門, 講師 (40807327)
• Project Period (FY): 2020-04-01 – 2022-03-31
• Keywords: 集中治療後症候群 / ICU獲得性筋力低下 / タンパク質 / 非窒素カロリー

Outline of Final Research Achievements

It is currently unclear worldwide whether intensive care patients should be given a large amount of protein early in life to maintain physical function, and the appropriate nutritional therapy after leaving the intensive care unit is also unknown. Therefore, in this study, we sought to determine what kind of diet, especially the balance of protein and non-protein calories, is consumed by patients who have to stay in the intensive care unit for more than 3 days before discharge from the hospital, and to clarify the relationship between the diet and physical function.

Free Research Field

麻酔科学

Academic Significance and Societal Importance of the Research Achievements

近年集中治療室入室患者の生存率は上昇している。一方で、集中治療を長期に必要とした患者様は四肢の筋力低下をきたす場合(集中治療後症候群,ICU獲得性筋力低下)があり1年後に半数程度介護支援が必要となることが過去の研究で報告されている。集中治療に関連する身体機能低下はその患者様やご家族のみならず、医療費や介護費の増加を通じて社会的にも問題であり、予防方法の解明は生存率が上昇している現在の集中治療において重要である。