2022 Fiscal Year Final Research Report
The predictive ability of soluble urokinase plasminogen activator receptor for elderly emergency patients.
| Project/Area Number |
20K17910
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 55060:Emergency medicine-related
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | suPAR / prognosis / preventable attendance / mortality / emergency department |
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| Outline of Final Research Achievements |
49 eligible older patients were included, and thirteen PEA cases were detected and eight patients died. The median suPAR was significantly lower in the PEA group and survivor’s group. The median (interquartile range) suPAR and NEWS were 9.0 ng/mL (5.6) and 4 (4.0). For suPAR, the AUC for the prediction of PEA was 0.678. Furthermore, the AUC for predicting PEA was 0.867 for suPAR + WBC + CRP + NEWS. Similarly, the AUC for the prediction of mortality was 0.805 in suPAR. The AUC of modified suPAR with NEWS for mortality was higher than that of suPAR and 0.865.
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| Free Research Field |
emergency medicine
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| Academic Significance and Societal Importance of the Research Achievements |
In Japan, the increase number of elderly emergency patients is a serious issue in emergency medicine, and as the results of this study show, if we could predict the unnecessary emergency attendance, it may be possible to alleviate emergency overcrowding in the future.
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