Hip osteoarthritis after spinopelvic fusion surgery

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K18008
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 56020:Orthopedics-related
• Research Institution: Wakayama Medical University
• Principal Investigator: Kozaki Takuhei 和歌山県立医科大学, 医学部, 博士研究員 (90838319)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: 成人脊柱変形手術 / 変形性股関節症 / 隣接関節障害

Outline of Final Research Achievements

Hip osteoarthritis progresses rapidly after adult spinal deformity surgery, which is one of the complications of this procedure, but its pathology has not been clearly understood. In this study, we used two three-dimensional evaluation methods, finite element analysis and motion analysis, to compare the stress on the hip joint before and after adult spinal deformity surgery. The finite element analysis showed hip joint stress increased much more in a spinopelvic fixation than the other model. Motion analysis also showed hip joint moment increased after surgery. These results demonstrated that hip osteoarthritis that progresses after adult spinal deformity surgery is adjacent joint damage caused by pelvic fixation.

Free Research Field

脊椎

Academic Significance and Societal Importance of the Research Achievements

成人脊柱変形術後の股関節症は新規発生率が20%であるものの、有効な治療法が確立されていない。本研究結果より本病態は骨盤固定に伴う隣接関節障害であることが判明した。本研究をもとに今後予防法を開発することが期待される。