2022 Fiscal Year Final Research Report
Investigation of minimally important differences for improving interpretability and development of a Web-based feedback system
Project/Area Number |
20K18962
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Research Category |
Grant-in-Aid for Early-Career Scientists
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Allocation Type | Multi-year Fund |
Review Section |
Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
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Research Institution | Okayama University |
Principal Investigator |
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Project Period (FY) |
2020-04-01 – 2023-03-31
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Keywords | ウェブシステム / 最小重要差 / 患者報告型アウトカム / 全身性エリテマトーデス / アンブレラレビュー |
Outline of Final Research Achievements |
Recently, the use of personal electronic devices such as personal computers and smart phones has widely spread. For the use of personally-owned devices in medical research, we have developed a web-based software system with functions for collecting survey data, summarizing the results, and providing feedback. This system uses Grafana, an advanced dashboard for viewing various database metrics via a web browser and provides an open platform for analysis, monitoring, and feedback. For feedback of the information to respondents and researchers, it is necessary to display summarized values along with the reference values ( minimally importtant differences) necessary for deciphering changes over time. In this study, the minimum significant difference was calculated by actually collecting the data of systemic lupus erythematosus (SLE) patients over time concurrent with the development of the system.
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Free Research Field |
膠原病・リウマチ学, 疫学
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Academic Significance and Societal Importance of the Research Achievements |
SLEに広く使用される生活の質(QOL)尺度の最小重要差を確立することには, 今後のQOL研究や新薬の効果を調査する臨床試験の解釈の指標を提供するうえで重要な価値がある。このような指標は臨床現場においても副腎皮質ステロイドの投与量を調整するための指標としても役立ち得る。オンラインでQOL調査が完了できれば, COVID-19および季節性インフルエンザ等の感染流行期にも病院を訪れる必要がなくなり, 調査機会の逸失を低減できるという利点がある. 即時フィードバック機能を備えることは回答のモチベーションを高めさらなる精緻かつ妥当な将来のQOL研究の実施に繋がることが期待できる.
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