2022 Fiscal Year Final Research Report
Development of the novel method for improving image quality in postmortem CT
| Project/Area Number |
20K18984
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 58040:Forensics medicine-related
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| Research Institution | Tohoku University (2022)
Tokyo Metropolitan University (2020-2021) |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | 死後CT / 画質改善 / 死亡時画像診断 / 複数回撮影 / 画像加算 |
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| Outline of Final Research Achievements |
This study aimed to develop a novel technique for enhancing the image quality of postmortem CT scans using a method called fused CT, which involves the summation of multiple images obtained from postmortem CT scans.
Through rigorous phantom experiments, it was successfully demonstrated that the fusion of images acquired from multiple scans effectively reduces noise without compromising resolution. Subsequently, during the examination of deceased cases, the need to improve contrast and resolution specifically for target organs was identified. Additional phantom experiments were conducted to explore the optimal settings of tube voltage and image reconstruction methods, resulting in significant improvements in both contrast and resolution.
As a result, this study has introduced a novel approach for enhancing the image quality of postmortem CT scans, surpassing previously unattainable levels in clinical practice, and thus advancing the forensic investigation of causes of death.
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| Free Research Field |
死亡時画像診断
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| Academic Significance and Societal Importance of the Research Achievements |
日本では死因究明に死亡時画像診断が応用されており、年間約15万件以上が画像検査による死因究明が実施されていると推測される。そのほとんどは死後CTが実施されているため、今回の画質改善によって死因究明の向上に寄与することができた。
さらに今回の開発は、大量のX線が照射されるため、生体での実験、検証は不可能であり、死後CTでしか達成することができなかった。生体でも体動がなく画質向上がメリットとなる症例においては、本手法の応用が可能であり、新たな画像診断の基準を検討する機会を提供する。
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