Estimation of maximum allowable weight gain due to smoking cessation using cardiovascular disease risk prediction model as an index

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K19205
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 58080:Gerontological nursing and community health nursing-related
• Research Institution: Osaka University (2022-2023); Shiga University of Medical Science (2020-2021)
• Principal Investigator: Godai Kayo 大阪大学, 大学院医学系研究科, 助教 (30708681)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: 禁煙 / 循環器疾患予防 / 体重増加

Outline of Final Research Achievements

Among the participants who underwent a medical examination sequentially more than four years, we extracted participants who have quit smoking for more than 3 years and matched the sex generation with them and randomly selected nonsmokers, smokers. The body weight gain one year after the smoking quitter was bigger than nonsmokers, smokers, but the weight gain of the smoking quitter remained to less than an average of 1.5kg. The weight gain slowed down after two years later, and the difference with nonsmokers, smokers was not found in body weight gain.
Blood pressure of one year later more greatly increased than nonsmokers, smokers in the smoking quitters whom weight one year later increased more than 5% in the men. However, the difference by the weight gain presence was not found after two years later. Also, in more than 5% of weight gain presence, the difference was not found in a change of the cardiovascular disease risk score.

Free Research Field

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Academic Significance and Societal Importance of the Research Achievements

禁煙推進は健康増進のため重要であるが、禁煙開始後には体重が増加することが知られており、過大な体重増加は循環器病リスクを高めることになりかねない。健診受診者を対象に禁煙者の体重変化を観察すると、体重増加の平均は1.5Kg程度にとどまっており、血圧や循環器病リスクへの明らかな影響は認められなかったことから、体重増加によらず禁煙にはメリットがあると改めて確認された。