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2023 Fiscal Year Final Research Report

The association of osteosarcopenia on future falls, fractures, and long-term care

Research Project

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Project/Area Number 20K19221
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 58080:Gerontological nursing and community health nursing-related
Research InstitutionJapan University of Health Sciences

Principal Investigator

Asahi Ryoma  日本保健医療大学, 保健医療学部理学療法学科, 講師 (60751724)

Project Period (FY) 2020-04-01 – 2024-03-31
Keywords骨粗鬆症 / サルコペニア / 転倒 / 骨折 / 地域在住中高年者
Outline of Final Research Achievements

During the 4-year follow-up period, 24 (3.6%) fractures occurred. The rates of fracture in each relevant group were 0% for sarcopenia, 6.6% for osteoporosis, and 22.2% for osteosarcopenia, with participants with osteoporotic sarcopenia having a significantly higher rate of fracture over the four-year period.
The fracture rate was significantly higher for osteosarcopenia, we suggested that the co-existense of osteoporosis and sarcopenia increases the risk of fracture. Interventions for osteoporosis or/and sarcopenia may reduce the risk of fracture, and to prevent for fracture is necessary to establish measures for osteosarcopenia.

Free Research Field

地域・老年看護学、応用健康科学

Academic Significance and Societal Importance of the Research Achievements

研究では、まず骨粗鬆症サルコペニアにおける身体機能、骨密度の特徴が明らかにした。骨粗鬆症サルコペニアの特徴を明らかにすることで、骨粗鬆症とサルコペニアの両方を考慮した対策を構築できると考える。さらに、骨折の有害事象と骨粗鬆症サルコペニアとの関係が明らかにした。骨粗鬆症だけでも骨折リスクは高まるものの、さらにサルコペニアを併発していると骨折の割合が約4倍も増加することが示唆れた。骨粗鬆症もしくはサルコペニアへの介入は、骨折リスクを減少させる可能性があり、改めて国内でも骨粗鬆症サルコペニアへの対策を構築するための基盤的研究となったと考える。

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Published: 2025-01-30  

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