Prevalence and infection source of Helicobacter pylori among residents and their environments in the Nara prefecture

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K19250
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 58080:Gerontological nursing and community health nursing-related
• Research Institution: Nara Medical University
• Principal Investigator: Horiuchi Saori 奈良県立医科大学, 医学部, 講師 (40794334)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: Helicobacter pylori / 感染源 / PCR

Outline of Final Research Achievements

We collected 40 environmental samples(29 environmental water and 11 fecal samples from dogs) and analyzed. Helicobacter pylori was not detected in the 40 samples. We amplified the 16S rRNA gene in the 11 fecal samples from dogs. Helicobacter canis was detected in three of the 11 fecal samples from dogs.
Colonies of Pseudomonas putida, P. aeruginosa, Aeromonas hydrophila, Rahnella aquatilis were isolated from the environmental water samples which were collected from lake, stream, and river.

Free Research Field

地域看護学

Academic Significance and Societal Importance of the Research Achievements

イヌや水検体からピロリ菌が検出されたという報告もあるが、本研究においてはピロリ菌は検出されず、感染源を特定することはできなかった。一方で、イヌの糞便からピロリ菌と同属のHelicobacter canisが検出された。Helicobacter canisはヒトへ感染し、菌血症の原因菌となることから、ピロリ菌と合わせて人獣共通感染症の観点から更なる調査が必要である。