2022 Fiscal Year Final Research Report
Development of the biomechanical simulation system for the analysis of the mechanism of injury for tenosynovitis
| Project/Area Number |
20K19362
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 59010:Rehabilitation science-related
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| Research Institution | Meijo University |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | 筋骨格モデル / 解剖体 / 有限要素シミュレーション / 腱鞘炎 |
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| Outline of Final Research Achievements |
In this study, we developed a biomechanical simulation system to elucidate the mechanism of tendinopathy by using mechanical measurements of soft tissues on cadaveric specimens and a finite element musculoskeletal model from the field of medical engineering. The material parameters for the finite element simulation were determined by conducting tensile tests of muscles and tendons in cadaveric forearms. Simulation analysis using the constructed musculoskeletal model showed that the load on the abductor pollicis longus tendon increased with wrist joint motion and forearm muscle contraction, consistent with the site of inflammation in de Quervain's tenosynovitis.
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| Free Research Field |
バイオメカニクス
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| Academic Significance and Societal Importance of the Research Achievements |
本研究では，ヒト解剖体を用いた力学試験や有限要素シミュレーションによって，前腕部腱鞘炎に関する力学的負荷を解析可能な筋骨格シミュレーションシステムを構築した．シミュレーション解析より，筋収縮運動によって腱部負荷が増大した箇所と，実際の症例における炎症部位が一致することが示され，これにより，様々な症例における力学的発生メカニズムの解明や，疾患の危険因子となる動作を予測可能であることが示唆された，さらに，将来的に症状改善のためのリハビリ指針の提案や，治療に有効な専用装具の開発などの医工連携分野への展開の可能性を示すことができた．
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