The elucidation the mechanism through which exercise improves adipose tissue metabolism

2022 Fiscal Year Final Research Report

• Project/Area Number: 20K19532
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 59020:Sports sciences-related
• Research Institution: Department of Clinical Research, National Hospital Organization Kyoto Medical Center
• Principal Investigator: Nirengi Shinsuke 独立行政法人国立病院機構(京都医療センター臨床研究センター), 臨床研究企画運営部, 研究員 (70741156)
• Project Period (FY): 2020-04-01 – 2023-03-31
• Keywords: 褐色脂肪組織 / 運動 / オキシリピン / 寒冷曝露

Outline of Final Research Achievements

We performed a lipidomics test and measured brown adipose tissue activity in college athletic non-athletic students. Interestingly, college athletes with high brown adipose tissue activity had elevated blood oxylipin levels after cold exposure. Next, we performed lipidomics and gene expression analysis of brown adipose tissue in mice after exercise and cold exposure. The results were presented at three international conferences.

Other things, A review paper on brown adipose tissue was accepted by Experimental Gerontology (published)

Free Research Field

運動生理学

Academic Significance and Societal Importance of the Research Achievements

運動をすることによる褐色脂肪組織への変化について検討を行った。
運動による健康増進効果への知見を深めることができた。