the usefulness of nutritional therapy for acute stroke patients

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K19651
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 59040:Nutrition science and health science-related
• Research Institution: Nippon Medical School
• Principal Investigator: Suzuki Kentaro 日本医科大学, 医学部, 講師 (20591259)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: 経腸栄養 / 脳卒中

Outline of Final Research Achievements

The aim of the study was to determine the safety of rapid administration of early enteral nutrition. From October 2019 to June 2020, a retrospective study was conducted to determine if there was a difference in the incidence of pneumonia, vomiting, and diarrhea, the major complications, between those who received rapid administration and those who received usual administration of enteral nutrition. Results from the study of 45 patients in the rapid administration group and 26 patients in the usual administration group showed no statistically significant difference in complication rates between the rapid and usual administration groups. The percentage of patients with at least one of the three complications was 49% in the rapid group and 54% in the standard group, indicating that the rapid group had fewer complications.　The results were published in the Journal of the neurological sciences.

Free Research Field

脳卒中

Academic Significance and Societal Importance of the Research Achievements

経腸栄養対象患者に早期から栄養を投与することは、医療スタッフの負担となるだけでなく、患者としても時間的に大きな負担となっていた。経腸栄養を迅速に投与することの安全性が証明されれば、病院側、患者側の両面に大きなメリットがあると考える。
本研究の結果をもとに、多施設共同ランダム化比較研究を行い、この結果の正当性を明らかにしたいと考えている。現在Rapid EN trialをおこなっており、今後に研究成果を発展させたいと考えている。