2023 Fiscal Year Annual Research Report
生物応用に向けた常温・常圧・水中ではたらく合成分子モーターの設計と合成
| Project/Area Number |
20K21131
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| Research Institution | Nara Institute of Science and Technology |
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Principal Investigator |
ラッペン ゲナエル 奈良先端科学技術大学院大学, 先端科学技術研究科, 教授 (60812576)
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| Co-Investigator(Kenkyū-buntansha) |
安原 主馬 奈良先端科学技術大学院大学, 先端科学技術研究科, 准教授 (90545716)
西野 智雄 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 (60824878)
尾本 賢一郎 奈良先端科学技術大学院大学, 先端科学技術研究科, 特任助教 (40820056) [Withdrawn]
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| Project Period (FY) |
2020-07-30 – 2024-03-31
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| Keywords | Molecular motors / Ruthenium complexes / Functionalization / Water soluble / Fluorescent tag / Amphiphile / Single molecule / membrane integration |
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| Outline of Annual Research Achievements |
The synthesis of the new target has been achieved with the formation of the amphiphilic molecular motor functionalized with a chemical tag. As tag, we derivatized a rhodamine fragment to be able to be attached to the amhiphilic motor.
Many attempts and catalytic systems where tested because the reactivity of the motor was drastically changed due to the presence of the long alkyl chains. The coupling reaction is now efficient and the target hybrid molecular motor was obtained and fully characterized including its emission properties.
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