2023 Fiscal Year Final Research Report

Development of new treatment methods, management and operation systems that enable multi-purpose use of cadavers.

Research Project

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Project/Area Number	20K21735
Research Category	Grant-in-Aid for Challenging Research (Exploratory)
Allocation Type	Multi-year Fund
Review Section	Medium-sized Section 58:Society medicine, nursing, and related fields
Research Institution	Nihon University (2021-2023) Aichi Medical University (2020)
Principal Investigator	HIRAI Shuichi 日本大学, 医学部, 教授 (70516054)
Co-Investigator(Kenkyū-buntansha)	大塚俊愛知医科大学, 医学部, 講師 (00879504) 河田晋一東京医科大学, 医学部, 助教 (00527955) 畑山直之愛知医科大学, 医学部, 准教授 (80534792) 林省吾東海大学, 医学部, 教授 (60349496) 梅本佳納榮愛知医科大学, 医学部, 助教 (80824945)
Project Period (FY)	2020-07-30 – 2024-03-31
Keywords	肉眼解剖学 / CST
Outline of Final Research Achievements	This study showed that the concentration of formalin in the tissues of urea-reperfused autopsies decreased in the urea-reperfused cadaver. Furthermore, it was showed that stiffness and Young's modulus of the femoral skin and artery were also lower. Evaluation from surgeons indicated the urea-reperfused cadaver was useful for surgical technique training. On the other hand, sufficient validity could not be obtained for organ stiffness and joint mobility. Technical staff commented that this method facilitates the management of dissected specimens, including number control, long-term preservation, and preparation as needed, since there is no need to switch to other treatment methods depending on the purpose, such as anatomy practice or surgical practice at the time of delivery. This study clarified the advantages and problems of urea treatment for multipurpose use.
Free Research Field	肉眼解剖学
Academic Significance and Societal Importance of the Research Achievements	遺体搬入時に、解剖体の利用目的を決定し処置方法を変更する現在のシステムに対して、「全ての遺体にホルマリン処置を行い保管管理し、利用直前に追加処置にて解剖体を至適状態にする」という新たな処置方法は、現行の施設、設備や遺体搬入手続きのまま、特殊な技能及び高価な試薬も必要としないため、長期保存が可能であり、解剖体数の管理が容易となり、効率よく解剖体を活用することが可能となる。本研究の成果は、解剖体の管理運用システムを大きく変革すると同時に、多くの大学で導入されることが期待される。