2022 Fiscal Year Final Research Report
Development of a non-invasive method for measuring oxygen uptake of active muscle using optical technology and elucidation of training effects
| Project/Area Number |
20K21772
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| Research Category |
Grant-in-Aid for Challenging Research (Exploratory)
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| Allocation Type | Multi-year Fund |
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| Review Section |
Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
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| Research Institution | Meiji University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
小野 弓絵 明治大学, 理工学部, 専任教授 (10360207)
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| Project Period (FY) |
2020-07-30 – 2023-03-31
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| Keywords | スポーツ生理学 / 生体医工学 / 有酸素性エネルギー代謝 / 末梢循環 / 光技術 |
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| Outline of Final Research Achievements |
In this study, to solve the problems of conventional measurement technique that have been a barrier to research on oxygen uptake in active muscles in humans, we developed a noninvasive continuous measurement technique of skeletal muscle tissue oxygen uptake employing diffusion correlation spectroscopy (DCS) and near-infrared spectroscopy (NIRS) and investigated its utility. The DCS-NIRS simultaneous measurement system developed in this study was shown to be capable of noninvasively and continuously measuring changes in oxygen uptake in active muscle. Furthermore, we confirmed that the DCS-NIRS simultaneous measurement system can clearly detect the temporal changes in active muscle oxygen uptake in response to voluntary exercise and involuntary exercise induced by electrical muscle stimulation and showed that the system can be applied to various studies in the field of sports physiology, exercise training and rehabilitation.
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| Free Research Field |
スポーツ生理学
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| Academic Significance and Societal Importance of the Research Achievements |
本研究において開発に成功したDCS-NIRS同時計測システムにより，これまで検出することが困難であった，活動筋における酸素供給および酸素消費の動態を非侵襲かつ連続的に測定することが可能となった。本研究の成果は，運動能力に直接影響する活動筋の酸素摂取量の動態や最大値を規定するメカニズムの解明に資するものである。さらに，トレーニングやリハビリテーションの効果の評価，運動不足，加齢，生活習慣病などの影響の検討，疾病の早期発見・予防・治療などへの応用などスポーツ生理学分野に留まらない広範な波及効果が期待できる。
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