Development of a histologically based lymphatic drainage method focusing on changes in lymphatic pathways due to dissection.

2021 Fiscal Year Final Research Report

• Project/Area Number: 20K23231
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Multi-year Fund
• Review Section: 0908:Society medicine, nursing, and related fields
• Research Institution: Komatsu University
• Principal Investigator: Suzuki Yuiko 公立小松大学, 保健医療学部, 助教 (40881983)
• Project Period (FY): 2020-09-11 – 2022-03-31
• Keywords: リンパ浮腫 / 迂回路 / リンパ流遮断 / ラット

Outline of Final Research Achievements

Three main results were obtained in the present study. First, the deep medial system, the superficial medial system, a connection between the superficial and deep medial lymphatic systems, and the superficial lateral system, were elucidated. Second, three types of detours, namely the detour of the lateral abdomen, the detour to the lymphatic vessel near the midline of the abdomen, and the detour to the contralateral inguinal lymph node, were identified after lymphatic flow blockage. Lastly, detours were located in the fatty layer above the panniculus carnosus muscle and their lumina were wide. The histology suggested that the detour was a pre-collecting lymphatic vessel. Lymphatic routes in the rat hindlimbs after lymphatic flow blockage were different from those of the normal rat lymphatic system.

Free Research Field

基礎看護学

Academic Significance and Societal Importance of the Research Achievements

ラット下肢のリンパ流遮断後のリンパ経路は、正常なラットのリンパ系とは異なっていた。このことから、リンパ遮断後に生じたリンパ経路に焦点化したリンパドレナージを行うことができれば、ケア時間の短縮を見込める可能性がある。このことは、患者のケア負担軽減、患者の社会進出を助けることができると考えられる。