Development of materials to promote explanation of effects of cancer treatment on reproductive function and fertility preservation

2022 Fiscal Year Final Research Report

• Project/Area Number: 20K23245
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Multi-year Fund
• Review Section: 0908:Society medicine, nursing, and related fields
• Research Institution: National Cancer Center Japan
• Principal Investigator: Okamura Masako 国立研究開発法人国立がん研究センター, がん対策研究所, 研究員 (90872804)
• Project Period (FY): 2020-09-11 – 2023-03-31
• Keywords: 思春期若年成人世代がん患者 / 生殖機能 / 妊孕性温存 / がん治療

Outline of Final Research Achievements

In 2020 and 2021, an interview survey was conducted with 16 doctors and 4 nurses who were involed in the treatment of adolescent and young adults (AYAs) with cancer. We also interviewed 10 AYAs with cancer. From 2021 to 2022, 30 interviewees' verbatim transcripts were analyzed by four analysts based on the Consolidated Framework for Implementation Research (CFIR), which is an integrated framework for implementation research.
As a result of analysis of the interview data with healthcare providers, barriers and facilitators of explanations about the effect of treatment on reproductive function and fertility preservation were clarified. In addition, the analysis of patient interview data revealed the patients' preferences regarding fertility care.

Free Research Field

精神腫瘍学

Academic Significance and Societal Importance of the Research Achievements

先行研究でAYA世代がん患者のニーズや実態調査が行われているが、話し合いを促進するための解決策は世界的にも提案されていない。本研究は患者に対する説明の際の阻害促進要因に着目し、医療者と患者を対象とした調査により要因を踏まえた説明促進資材を開発する点で学術的意義が高いと言える。
本研究の成果により妊孕性ケアの阻害促進要因と患者の意向が明らかとなり、説明とケアを促進する患者側と医療者側への介入開発に繋がっている。第４期がん対策推進基本計画のがん医療分野の目標の一つである妊孕性温存療法に関する提供体制の充実に向け、患者の意向に沿った妊孕性ケアを届けるための取り組みに貢献する。