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2014 Fiscal Year Final Research Report

Development and Efficient Production of Organosulfur and Organophosphorus Compounds by Transition Metal Catalyzed Method

Research Project

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Project/Area Number 21229001
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Chemical pharmacy
Research InstitutionTohoku University

Principal Investigator

YAMAGUCHI Masahiko  東北大学, 薬学研究科(研究院), 教授 (30158117)

Co-Investigator(Renkei-kenkyūsha) AN Zenjian  東北大学, 大学院薬学研究科, 研究助教 (80532176)
SHIGENO Masanori  東北大学, 大学院薬学研究科, 助教 (30571921)
ICHINOSE Wataru  東北大学, 大学院薬学研究科, 研究助教 (00636409)
SAITO Nozomi  東北大学, 大学院薬学研究科, 研究助教 (40636411)
LI Guanzou  東北大学, 大学院薬学研究科, 研究助教 (90714824)
Project Period (FY) 2009-04-01 – 2015-03-31
Keywords有機ヘテロ元素化合物 / 遷移金属触媒 / 平衡制御 / 非平衡熱力学系 / 省エネルギー
Outline of Final Research Achievements

Conventional synthetic methods for organoheteroatom compounds used for drugs and materials often involve use of large amount of energy and resources. Activation of reactants is generally conducted by highly reactive reagents, which is accompanied by the formation of large amounts of waste materials. It is then highly desirable to develop efficient synthetic methods for the production of useful organoheteroatom compounds.
This research is conducted to develop efficient catalysts and equilibrium control methods for such purpose. With regard to the synthesis of organosulfur and organophosphorus compounds, followings were examined: 1) development of active catalysts; 2) development of catalytic equilibrium control methods; 3) systematic synthesis of heterocyclic compounds; 4) development of novel drugs and materials; 5) transition-metal-catalyzed regeneration of rough materials.

Free Research Field

有機化学

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Published: 2016-06-03  

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