2012 Fiscal Year Final Research Report
Design of Biomaterials Platform which responds to Oxidative Stress
| Project/Area Number |
21240050
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YOSHITOMI Toru 筑波大学, 数理物質系, 研究員 (20585799)
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| Project Period (FY) |
2009 – 2012
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| Keywords | ナノメディシン / DDS / イメージング / 細胞培養床 / 活性酸素種 / 酸化ストレス |
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| Research Abstract |
Stable nitroxide radical-containing redox polymers, which we designed in this study, were found to effectively scavenge excessively generated reactive oxygen species and can be regarded as one of candidates for novel biomaterials.
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[Journal Article] Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid
Author(s)
Hiroto Hatakeyama, Hidetaka Akita, Erika Itoh, Yasuhiro Hayashi, Motoi Oishi, Yukio Nagasaki, R. Danev, K. Nagayama, N. Kaji, H. Kikuchi, Y. Baba, Harashima H
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Journal Title
Biomaterials
Volume: 32(18)
Pages: 4
DOI
Peer Reviewed
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