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2011 Fiscal Year Final Research Report

Fabrication of Nano channel for single bio-molecule analysis

Research Project

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Project/Area Number 21241032
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Nanomaterials/Nanobioscience
Research InstitutionOsaka University

Principal Investigator

KAWAI Tomoji  大阪大学, 産業科学研究所, 特任教授(常勤) (20092546)

Co-Investigator(Kenkyū-buntansha) TANIGUCHI Masateru  大阪大学, 産業科学研究所, 教授 (40362628)
TANAKA Hiroyuki  大阪大学, 産業科学研究所, 助教 (20314429)
Co-Investigator(Renkei-kenkyūsha) YANAGIDA Takeshi  大阪大学, 産業科学研究所, 准教授 (50420419)
Project Period (FY) 2009 – 2011
Keywords1分子科学 / 単一バイオ分子 / ナノチャネル構造
Research Abstract

Nano channel structure realized the system which detects a single bio-molecule. By using nano channel structure, it becomes possible to introduce a bio-molecule to measure with a desired time scale into the position of a wish. It is expected that a series of results will develop into the nano-biotechnology research based on future one-molecule analysis technology greatly.

  • Research Products

    (52 results)

All 2012 2011 2010 2009

All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (40 results)

  • [Journal Article] Electrical Detection of Single Methylcytosines in a DNA Oligomer2011

    • Author(s)
      M. Tustsui, K. Matsubara, T. Ohshiro, M. Furuhashi, M. Taniguchi, T. Kawai
    • Journal Title

      J ACS

      Volume: Vol.133、No.23 Pages: 9124-9128

    • Peer Reviewed
  • [Journal Article] Single-Molecule Sensing Electrode Embedded in-plane Nanopore2011

    • Author(s)
      M. Tustsui, S. Rahong, Y. Iizumi, T. Okazaki, M. Taniguchi, T. Kawai
    • Journal Title

      Scientific Reports

      Volume: Vol.1 Pages: 1-6

    • Peer Reviewed
  • [Journal Article] Dopant Homogeneity and Transport Properties of Impurity-doped Oxide Nanowires2011

    • Author(s)
      A. Klamchuen, T. Yanagida, M. Kanai, K. Nagashima, K. Oka, S. Seki, M. Suzuki, Y. Hidaka, S. Kai, T. Kawai
    • Journal Title

      Appl. Phys. Lett.

      Volume: Vol.98、No.5 Pages: 053107(1-3)

    • Peer Reviewed
  • [Journal Article] Molecule-Electrode Bonding Design for High Single-Molecule Conductance2010

    • Author(s)
      K. Yokota, M. Taniguchi, M. Tsutsui, T. Kawai
    • Journal Title

      JACS

      Volume: Vol.132、No.49 Pages: 17364-17365

    • Peer Reviewed
  • [Journal Article] Atomically Controlled Fabrications of Subnanometer Scale Electrode Gaps2010

    • Author(s)
      M. Tsutsui, T. Ohshiro, K. Matsubara, M. Furuhashi, M. Taniguchi, T. Kawai
    • Journal Title

      J. Appl. Phys.

      Volume: Vol.108、No.6 Pages: 064312(1-4)

    • Peer Reviewed
  • [Journal Article] Mechanically-Controllable Single Molecule Switch Based on Configuration Specific Electrical Conductivity of Metal-Molecule-Metal Junctions2010

    • Author(s)
      M. Taniguchi, M. Tsutsui, K. Yokota, T. Kawai
    • Journal Title

      Chem. Sci.

      Volume: Vol.1、No.2 Pages: 247-253

    • Peer Reviewed
  • [Journal Article] Identifying Single Nucleotides by Tunnelling Current2010

    • Author(s)
      M. Tsutsui, M. Taniguchi, K. Yokota, T. Kawai
    • Journal Title

      Nature Nanotech.

      Volume: Vol.5、No.4 Pages: 286-290

    • Peer Reviewed
  • [Journal Article] Role of Surrounding Oxygen on Oxide Nanowire Growth2010

    • Author(s)
      A. Klamchuen, T. Yanagida, M. Kanai, K. Nagashima, K. Oka, T. Kawai, M. Suzuki, Y. Hidaka, S. Kai
    • Journal Title

      Appl. Phys. Lett.

      Volume: Vol.97、No.7 Pages: 073114(1-3)

    • Peer Reviewed
  • [Journal Article] Impurity Induced Periodic Mesostructures in Sb-doped SnO_2 Nanowires2010

    • Author(s)
      A. Klamchuen, T. Yanagida, M. Kanai, K. Nagashima, K. Oka, T. Kawai, M. Suzuki, Y. Hidaka, S. Kai
    • Journal Title

      J. Crystal Growth

      Volume: Vol.312、No.21 Pages: 3251-3256

    • Peer Reviewed
  • [Journal Article] Identifying Single Nucleotides by Tunnelling current2010

    • Author(s)
      M. Tsutsui, M. Taniguchi, K. Yokota, T. Kawai
    • Journal Title

      Nature Nanotech.

      Volume: VoL. 5、No.4 Pages: 286-290

    • Peer Reviewed
  • [Journal Article] Fabrication of the Gating Nanopore2009

    • Author(s)
      M. Taniguchi, M. Tsutsui, K. Yokota, T. Kawai
    • Journal Title

      Appl. Phys. Lett.

      Volume: Vol.95 Pages: 123701(1-3)

    • Peer Reviewed
  • [Journal Article] Partial Sequencing of a Single DNA Molecule with a Scanning Tunnelling Microscope2009

    • Author(s)
      Hiro. Tanaka, T. Kawai
    • Journal Title

      Nature Nanotech.

      Volume: Vol.4、No.8 Pages: 518-522

    • Peer Reviewed
  • [Presentation] ゲーティングナノポアによる1分子DNAシークエンシング2012

    • Author(s)
      川合知二
    • Organizer
      平成23年度中部地区ナノネット報告会
    • Place of Presentation
      自然科学研究機構・岡崎コンファレンスセンター(愛知県・岡崎市)
    • Year and Date
      2012-03-31
  • [Presentation] Innovative Nano-Biodevices for DNA and related molecules : STM and Gating Nanopore2012

    • Author(s)
      T. Kawai
    • Organizer
      DNA Nanotechnology : From Structure to Function
    • Place of Presentation
      中国科学院上海応用物理研究所, Astor House Hotel(Shanghai・China)
    • Year and Date
      2012-03-18
  • [Presentation] Gating-Nanopores for Single Molecule DNA Sequencing2012

    • Author(s)
      T. Kawai
    • Organizer
      Nanopores Conference 2012-Zing conferences
    • Place of Presentation
      Hesperia Lanzarote(Lanzarote・Spain)
    • Year and Date
      2012-02-08
  • [Presentation] 単一分子DNAのナノポアシークエンシング2012

    • Author(s)
      田中裕行
    • Organizer
      JSTさきがけ「界面の構造と制御」研究領域公開シンポジウム界面科学のフロンティア~計測・デバイス・生体界面の分野横断と新展開~
    • Place of Presentation
      東北大学片平キャンパス(宮城県・仙台市)
    • Year and Date
      2012-01-05
  • [Presentation] Fabrication Method of Plastic Micropores for Artificial Lipid Bilayer Formation2011

    • Author(s)
      田中裕行
    • Organizer
      ICSPM19
    • Place of Presentation
      北海道洞爺湖万世閣(北海道・虻田郡)
    • Year and Date
      2011-12-19
  • [Presentation] Innovative Nano-Biodevices for DNA and related molecules : STM and Gating Nanopore2011

    • Author(s)
      T. Kawai
    • Organizer
      北海道大学電子科学研究所国際シンポジウム
    • Place of Presentation
      Chateraise Gateaux Kingdom Sapporo(北海道・札幌市)
    • Year and Date
      2011-11-22
  • [Presentation] Nanotechnology for Single Molecular DNA Sequencing-STM and Gating Nanopore-2011

    • Author(s)
      T. Kawai
    • Organizer
      DPS2011
    • Place of Presentation
      ホテル京都ガーデンパレス(京都府・京都市)
    • Year and Date
      2011-11-11
  • [Presentation] Nanotechnology for Single Molecular DNA Sequencing-STM and Gating Nanopore-2011

    • Author(s)
      T. Kawai
    • Organizer
      7th Handai Nanoscience and Nanotechnology International Symposium-Nanoscience and Nanotechnology in the Next Ten Years
    • Place of Presentation
      大阪大学銀杏会館(大阪府・吹田市)
    • Year and Date
      2011-11-11
  • [Presentation] 核酸塩基分子の単分子識別-3世代DNAシーケンサーに向けて2011

    • Author(s)
      M. Taniguchi
    • Organizer
      SCE2011第31回キャピラリー電気泳動シンポジウムin TSURUOKA
    • Place of Presentation
      鶴岡メタボロームキャンパス(山形県・鶴岡市)
    • Year and Date
      2011-11-10
  • [Presentation] Innovative Nano-Biodevices for DNA and related molecules : STM and Gating Nanopore2011

    • Author(s)
      T. Kawai
    • Organizer
      ASIASENSE 2011
    • Place of Presentation
      The Shilla(Jeju・Korea)
    • Year and Date
      2011-10-26
  • [Presentation] Scanning Probe Microscope for DNA Sequencing and Cell Surgery2011

    • Author(s)
      T. Kawai
    • Organizer
      The Korean Physical Society Autumn Meeting 2011
    • Place of Presentation
      BEXCO(Busan・Korea)
    • Year and Date
      2011-10-20
  • [Presentation] Gating Nanopores for Single-Molecule DNA Electrical Sequencing2011

    • Author(s)
      T. Kawai
    • Organizer
      IEEE NMDC 2011
    • Place of Presentation
      The Shilla(Jeju・Korea)
    • Year and Date
      2011-10-19
  • [Presentation] Mechanical Controlled BreakJunction to Gating Nanopore forSingle Biomolecule ElectricalSequencing2011

    • Author(s)
      T. Kawai
    • Organizer
      ACSIN 2011
    • Place of Presentation
      Sokos Hotel Olympia Garden(St. Petersburg・Russia)
    • Year and Date
      2011-10-04
  • [Presentation] Development of Gating Nanopores for Next-Next DNA Sequencing using Mechanically Controllable Break-Junctions2011

    • Author(s)
      M. Taniguchi
    • Organizer
      ASME-JSME-KSME Jpint Fluids Engineering Conference 2011
    • Place of Presentation
      ACTY CITY Congress Center(静岡県・浜松市)
    • Year and Date
      2011-07-26
  • [Presentation] 次々々世代シークエンサー開発の最先端:ナノポアデバイス開発2011

    • Author(s)
      川合知二
    • Organizer
      ゲノムコンファレンス
    • Place of Presentation
      大阪大学テクノアライアンス棟(大阪府・吹田市)
    • Year and Date
      2011-07-20
  • [Presentation] Gating Nanopores for Single-Molecule DNA Electrical Sequencing2011

    • Author(s)
      T. Kawai
    • Organizer
      ARCEI. ORG Jointly Presents, Fourth International Epigenomics, Sequencing & SNiPs-2011
    • Place of Presentation
      The Joseph B. Martin Conference Center at Harvard Medical School(Boston・USA)
    • Year and Date
      2011-07-12
  • [Presentation] 次々世代シークエンサー開発の最前線:ナノポアデバイス開発2011

    • Author(s)
      川合知二
    • Organizer
      ゲノムコンファレンス次n世代シークエンス技術がもたらす新潮流
    • Place of Presentation
      東京ガーデンパレス(東京都・文京区)
    • Year and Date
      2011-06-30
  • [Presentation] Partial Sequencing of a Single DNA Molecule with a Scanning Tunnelling Microscope2011

    • Author(s)
      Hiro. Tanaka
    • Organizer
      Osaka University-RUG symposium entitled" Bio-inspired Materials and Functionalities"
    • Place of Presentation
      Hampshire Hotel Plaza(Groningen・Netherlands)
    • Year and Date
      2011-06-21
  • [Presentation] Gating Nanopores for Single-Molecule DNA Electrical Sequencing2011

    • Author(s)
      T. Kawai
    • Organizer
      ISMM 2011 in Conjunction with the KBCS Spring Meeting
    • Place of Presentation
      GaYaGeum Hall in the Hotel Seoul Kyoyuk Munhwa Hoekwan(Seoul・Korea)
    • Year and Date
      2011-06-03
  • [Presentation] 1分子計測技術でDNAを観る2011

    • Author(s)
      川合知二
    • Organizer
      日本学術会議・科学技術振興機構公開シンポジウム観る、測る、そして知る-最先端計測・分析技術が拓く世界-
    • Place of Presentation
      日本学術会議講堂、(東京都・港区)
    • Year and Date
      2011-05-20
  • [Presentation] Gating Nanopores for Single-Molecule DNA Electrical Sequencing2011

    • Author(s)
      T. Kawai
    • Organizer
      韓国陶磁器学会
    • Place of Presentation
      京畿大学校(韓国・水原市)
    • Year and Date
      2011-04-21
  • [Presentation] Development of Gating Nanopores for Single-Molecule DNA Electrical Sequencing2011

    • Author(s)
      T. Kawai
    • Organizer
      NHGRI Advanced Sequencing Technology Development Meeting
    • Place of Presentation
      Catamaran Resort/ Hotel(San Diego・USA)
    • Year and Date
      2011-04-07
  • [Presentation] 1分子解析技術による次々世代DNAシーケンサーの開発2011

    • Author(s)
      谷口正輝
    • Organizer
      (社)日本表面科学会第69回表面科学研究会「単一分子の表面科学」
    • Place of Presentation
      東京工業大学デジタル多目的ホール(東京都・目黒区)
    • Year and Date
      2011-03-09
  • [Presentation] Development of Gating Nanopores for Single-Molecule Electrical Sequencing2011

    • Author(s)
      M. Taniguchi
    • Organizer
      ISSMA 2011
    • Place of Presentation
      国立京都国際会議場(京都府・京都市)
    • Year and Date
      2011-01-24
  • [Presentation] Toward 1000 Dollars Single Molecular DNA Sequencing-STM and Gating Nanopore-2011

    • Author(s)
      T. Kawai
    • Organizer
      2011 Japan-Taiwan Join Workshop on Bioelectronics
    • Place of Presentation
      国立成功大学(Tainan・Taiwan)
    • Year and Date
      2011-01-20
  • [Presentation] Green Nanotechnology for Low Power Consumption Devices using Metal Oxide Nanowires2010

    • Author(s)
      T. Kawai
    • Organizer
      IUMRS-ICEM2010
    • Place of Presentation
      KINTEX(Seoul・Korea)
    • Year and Date
      20100822-27
  • [Presentation] ゲーティングナノポアによる単分子解析2010

    • Author(s)
      谷口正輝
    • Organizer
      M & BE研究会「有機分子・バイオエレクトロニクスの新潮流」
    • Place of Presentation
      東北大学多元物質科学研究所(宮城県・仙台市)
    • Year and Date
      20100618-19
  • [Presentation] Single Biomolecule Spectroscopy and Conductance Measurement by Nanoelectrodes Systems2010

    • Author(s)
      M. Tsutusi
    • Organizer
      The 9th Japan France Workshop on Nanomaterials
    • Place of Presentation
      Mercure Hotel(Toulouse・France)
    • Year and Date
      2010-11-25
  • [Presentation] トンネル電流を用いたRNA分子の識別2010

    • Author(s)
      古橋匡幸
    • Organizer
      第71回応用物理学会学術講演会
    • Place of Presentation
      長崎大学文教キャンパス(長崎県・長崎市)
    • Year and Date
      2010-09-16
  • [Presentation] トンネル電流を指標とした生理活性核酸分子の単分子計測2010

    • Author(s)
      大城敬人
    • Organizer
      第71回応用物理学会学術講演会
    • Place of Presentation
      長崎大学文教キャンパス(長崎県・長崎市)
    • Year and Date
      2010-09-16
  • [Presentation] 2探針電流計測によるヌクレオチド単一分子識別2010

    • Author(s)
      筒井真楠
    • Organizer
      第71回応用物理学会学術講演会
    • Place of Presentation
      長崎大学文教キャンパス(長崎県・長崎市)
    • Year and Date
      2010-09-16
  • [Presentation] ナノポアによる1分子DNAシークエンシング2010

    • Author(s)
      谷口正輝
    • Organizer
      革新ナノバイオデバイス研究センターセミナー
    • Place of Presentation
      名古屋大学大学院工学研究科(愛知県・名古屋市)
    • Year and Date
      2010-07-07
  • [Presentation] Self-Assembled Metal Oxide Nanowires : Synthesis2010

    • Author(s)
      T. Kawai
    • Organizer
      Properties and Non-Voltile Memory Applciations、3rd International Conference on Nanostructures SElf-Assembly NanoSEA 2010
    • Place of Presentation
      Oustau Calendal Congress Center(Cassis・French Riviera)
    • Year and Date
      2010-06-28
  • [Presentation] Scientific Challenges for the Future of Nanotechnology2010

    • Author(s)
      T. Kawai
    • Organizer
      US-Japan-Korea-Taiwan Workshop on" Long-term Impacts and Future Opportunities for Technology"
    • Place of Presentation
      つくば国際会議場(茨城県・つくば市)
    • Year and Date
      2010-06-26
  • [Presentation] Sequencing of a Single DNA Molecule with a Scanning Tunneling Microscope2010

    • Author(s)
      Hiro. Tanaka
    • Organizer
      Functionalized Nanomaterials
    • Place of Presentation
      Santa Fe, New Mexico, USA
    • Year and Date
      2010-04-26
  • [Presentation] ゲーティングナノポアを用いた1分子検出2010

    • Author(s)
      谷口正輝
    • Organizer
      バイオ・マイクロシステム研究会、電気学会研究会
    • Place of Presentation
      名古屋大学(愛知県・名古屋市)
    • Year and Date
      2010-01-29
  • [Presentation] DNAの蛍光バイオナノサイエンス2010

    • Author(s)
      田中裕行
    • Organizer
      応用物理学会関西支部第2回(2009年度)支部貢献賞授賞式および平成21年度第2回講演会「蛍光技術とその応用」
    • Place of Presentation
      大阪大学中之島センター(大阪府・大阪市)
    • Year and Date
      2010-01-22
  • [Presentation] Identification of Single Nucleotides Using Gating Nanopores2010

    • Author(s)
      M. Taniguchi
    • Organizer
      13th SANKEN International Symposium 2010
    • Place of Presentation
      関西空港国際会議場(大阪府・泉佐野市)
    • Year and Date
      2010-01-19
  • [Presentation] Partial Sequencing of a Single DNA Molecule with a Scanning Tunnelling Microscope2009

    • Author(s)
      Hiro. Tanaka
    • Organizer
      ICSPM17
    • Place of Presentation
      熱川ハイツ(静岡県・賀茂郡)
    • Year and Date
      2009-12-10
  • [Presentation] Green NanoScience and Nanotechnology for the Energy Saving and Human Health2009

    • Author(s)
      T. Kawai
    • Organizer
      GJ-NST 2009
    • Place of Presentation
      JeollaNam-Do Provincial Government Hall(Muan・Korea)
    • Year and Date
      2009-11-05

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Published: 2013-07-31  

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