Visual Servo Microscope for Analysis of Animal Behavior

2012 Fiscal Year Final Research Report

• Project/Area Number: 21246040
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Intelligent mechanics/Mechanical systems
• Research Institution: Tohoku University
• Principal Investigator: KOICHI Hashimoto 東北大学, 大学院・情報科学研究科, 教授 (80228410)
• Project Period (FY): 2009 – 2012
• Keywords: 情報機器 / 知能機械システム

Research Abstract

We have developed a microscope system that tracks a target animal motion by using real-time control of motorized stage. The system can analyze and record the response of the target animal with high time and space resolutions. Especially, we have realized a system to observe C. elegans in bright field as well as in fluorescence images simultaneously. C. elegans is widely used for many purpose as a model animal. Thus the system is contributing in many fields including sensor response, neural network analysis, internal neural state analysis, motor control, and also animal behavior.

Research Products

• [Journal Article] Estimating Deformation of Neurons in Fluorescent Images (2012)
  • Author(s): Fei, X., Teramoto, T., Ishihara, T. and Hashimoto, K.
  • Journal Title: Interdisciplinary Information Sciences Volume: 18(2) Pages: 113-122
  • DOI: doi:10.4036/iis.2012.113
  • Peer Reviewed
• [Journal Article] Stability of switched stochastic systems in discrete-time (2011)
  • Author(s): Iwatani, Y., Arai, S. and Hashimoto, K.
  • Journal Title: SICE Journal of Control, Measurement, and System Integration Volume: 3(5) Pages: 368-371
  • Peer Reviewed
• [Journal Article] A condition for better estimation using asynchronous sampling than synchronous sampling (2011)
  • Author(s): Arai, S., Iwatani, Y. and Hashimoto, K.
  • Journal Title: SICE Journal of Control, Measurement, and System Integration Volume: 4(3) Pages: 249-253
  • Peer Reviewed
• [Journal Article] 細胞の個体差に適応する高速オートフォーカス顕微鏡 (2011)
  • Author(s): 小原健, 五十嵐康伸, 橋本浩一
  • Journal Title: 計測自動制御学会論文集 Volume: 47(1) Pages: 31-39
  • Peer Reviewed
• [Journal Article] Fast Sensor Scheduling for Spatially Distributed Sensors (2011)
  • Author(s): Arai, S., Iwatani Y. and Hashimoto, K.
  • Journal Title: IEEE Transactions on Automatic Control Volume: 56(8) Pages: 1900-1905
  • DOI: doi:10.1109/TAC.2011.2141450
  • Peer Reviewed
• [Journal Article] A Parallel Computation of the Region-Based Level Set Method for Boundary Detection with Moving Objects (2009)
  • Author(s): Fei, X., Igarashi, Y., Shinkai, M., Ishikawa, M. and Hashimoto, K.
  • Journal Title: Journal of Robotics and Mechatronics Volume: 21 Pages: 698-708
  • Peer Reviewed
• [Presentation] Exploration of Brain Function through Behavior (2012)
  • Author(s): Hashimoto, K. and Fei, X.
  • Organizer: Neural Activity Observation, and Optogenetic Manipulation. Invited Talk, International Symposium Optomechatronic Technologies (ISOT 2012)
  • Place of Presentation: France
  • Year and Date: 2012-09-29
• [Presentation] A virtual reality running machine for worms-a highly integrated system for olfactory behavior (2012)
  • Author(s): Tanimoto, Y., Yamazoe, A., Hashimoto, K. and Kimura, K.
  • Organizer: 5th East Asia C. elegans Meeting, 4-O06
  • Place of Presentation: Taipei, Taiwan
  • Year and Date: 2012-06-30
• [Presentation] Neurite fluorescence imaging of freely moving individual C. elegans animals with high-speed tracking and autofocus system (2012)
  • Author(s): Yokoyama, G., Tsukada, Y., Chen, M., Hashimoto, K. and Mori, I.
  • Organizer: 5th East Asia C. elegans Meeting, P-56
  • Place of Presentation: Taipei, Taiwan
  • Year and Date: 2012-06-30
• [Presentation] A virtual reality running machine for worms-a highly integrated system for olfactory behavior (2012)
  • Author(s): Tanimoto, Y., Yamazoe, A., Hashimoto, K. and Kimura, K.
  • Organizer: EMBL Conference C. elegans Neurobiology, P-126
  • Place of Presentation: Heidelberg, Germany
  • Year and Date: 2012-06-17
• [Presentation] High-speed tracking system for neurite fluorescence imaging during freely moving C. elegans. (2012)
  • Author(s): Tsukada, Y., Chen, M., Yokoyama, G., Hashimoto, K. and Mori, I.
  • Organizer: EMBL Conference C. elegans Neurobiology, P-196
  • Place of Presentation: Heidelberg, Germany
  • Year and Date: 2012-06-17
• [Presentation] Camera Localization by CAD Model Matching (2011)
  • Author(s): Zang, C. and Hashimoto, K.
  • Organizer: 2011 IEEE/SICE International Symposium on System Integration (SII 2011)
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2011-12-20